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Atomic Force Microscopy

Main applications

Atomic force microscopy has recently opened a variety of novel possibilities for imaging and manipulating cell surfaces in their native environment, thereby complementing optical imaging techniques.

While AFM imaging offers a means to visualize cell surface structure at nanometer resolution and in physiological conditions, AFM force spectroscopy allows researchers to localize single cell surface receptors and to quantitatively probe cellular interactions.

  • Nanoscale surface imaging of live cells and biosurfaces
  • Detection, localization and conformational analysis of single molecules

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Equipment

  • BioScope Catalyst (Bruker)/Observer Z1 (Zeiss)
  • BioScope Resolve (Bruker)/Observer Z1 (Zeiss)
  • NanoWizard III (JPK)/Observer Z1 (Zeiss)

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