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- 骋茅谤补濒诲颈苍别 Laloux
骋茅谤补濒诲颈苍别 Laloux
Professeure
Chercheuse qualifi茅e FNRS
Current positions
Since 2024: WELBIO Investigator, WEL Research Institute, Belgium
Since 2022: Associate Professor, UCLouvain
Since 2017: Research Associate (Chercheur Qualifi茅),听F.R.S.-FNRS听
Previous positions
2017 - 2022: Assistant Professor, UCLouvain
2013 - 2017: Post-doctoral researcher, group of Prof. J.-F. Collet, UCLouvain, Belgium (bacterial envelope stress responses)
2010 - 2013: Post-doctoral researcher, group听of Prof. C. Jacobs-Wagner, Yale University, New Haven, CT, USA听(bacterial cell cycle and polarity)
2005 - 2009: PhD student, group of Prof. X. De Bolle, UNamur, Belgium听(host-pathogen interactions)
2005: Master student intern, group of Prof. M. Vidal, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA听(interactomics)
Education
2009: PhD in Sciences, UNamur
2005: Master in Molecular and Cellular Biology,听UNamur听
2003: Bachelor in Biological sciences, UNamur
Major awards and grants
2024 - 2028: WELBIO Investigator Programme (WEL Research Institute, BE), Starting Grant
2023 - 2026: Projet de Recherche PDR F.R.S.-FNRS "Predator Division"
2022 - 2026: Actions de Recherche Concert茅e "PAChIDERM"
2022 - 2023: Cr茅dit de Recherche CDR F.R.S.-FNRS "Predator nucleoid"
2021: Fondation Louvain, Fonds Jacques Moulaert
2019 - 2024: ERC Starting Grant PREDATOR
2018: Fund Maurange Award, King Baudoing Foundation, Belgium
2018 - 2019: Mandat d'Impulsion Scientifique MIS F.R.S.-FNRS听"Micro-Predator"
2017: Alvarenga de Piauhy Award, Royal Academy of Medicine, Belgium
2005: "Prix Bauchau" for the Best Master thesis in Biology, promotions 2004 & 2005, UNamur, Belgium
Fellowships
2014 - 2017: F.R.S.-FNRS Post-doctoral fellowship (Charg茅 de Recherche)
2011 : van Itallie Fellow of the Belgian American Educational Foundation
2005 - 2009: F.R.S.-FNRS Research Fellow (Aspirant)
- 顿颈辫濒么尘别蝉
础苍苍茅别 Label Institution 2005 Licence en Sciences Biologique 贵补肠耻濒迟茅蝉 Universitaires Notre Dame de la Paix 脿 Namur 2009 Docteur en sciences 贵补肠耻濒迟茅蝉 Universitaires Notre Dame de la Paix 脿 Namur
LBIO1323 - Signalisation mol茅culaire (Faculty of Sciences, UCLouvain)
LBBMC2107 - Microbial Physiology (Faculty of Sciences, UCLouvain)
WSBIM1382 - G茅n茅tique et biotechnologie appliqu茅es (Faculty of Pharmacy and Biomedical Sciences, UCLouvain)
WSBIM2115 - Protein structure and function (Faculty of Pharmacy and Biomedical Sciences, UCLouvain)
听
- Les cours
Lab website :听
Group page on the de Duve Institute website :听
听
听
2023
Kaljevic, Jovana ; Tesseur, Coralie ; Le, Tung B K ; Laloux, 骋茅谤补濒诲颈苍别. Cell cycle-dependent organization of a bacterial centromere through multi-layered regulation of the ParABS system.. In: PLoS genetics, Vol. 19, no.9, p. e1010951 (2023). doi:10.1371/journal.pgen.1010951.
2023
Santin, Yoann ; Lamot, Thomas ; van Raaphorst, Renske ; Kaljevic, Jovana ; Laloux, 骋茅谤补濒诲颈苍别. Modulation of prey size reveals adaptability and robustness in the cell cycle of an intracellular predator.. In: Current biology : CB, Vol. 33, no.11, p. 2213-2222.e4 (2023). doi:10.1016/j.cub.2023.04.059.
2023
Rueff, Anne-St茅phanie ; van Raaphorst, Renske ; Aggarwal, Surya D ; Santos-Moreno, Javier ; Laloux, 骋茅谤补濒诲颈苍别 ; Schaerli, Yolanda ; Weiser, Jeffrey N ; Veening, Jan-Willem. Synthetic genetic oscillators demonstrate the functional importance of phenotypic variation in pneumococcal-host interactions.. In: Nature communications, Vol. 14, no.1, p. 7454 [1-12] (2023). doi:10.1038/s41467-023-43241-y.
2023
Maccioni, Luca ; Kasavuli, Joyce ; Leclercq, Sophie ; Pirlot, Boris ; Laloux, 骋茅谤补濒诲颈苍别 ; Horsmans, Yves ; Leclercq, Isabelle ; Schnabl, Bernd ; St盲rkel, Peter. Toll-like receptor 2 activation in monocytes contributes to systemic inflammation and alcohol-associated liver disease in humans.. In: Hepatology communications, Vol. 7, no.5, p. - (2023). doi:10.1097/HC9.0000000000000107.
2022
Remy, Oph茅lie ; Lamot, Thomas ; Santin, Yoann ; Kaljevic, Jovana ; de Pierpont, Charles ; Laloux, 骋茅谤补濒诲颈苍别. An optimized workflow to measure bacterial predation in microplates.. In: STAR protocols, Vol. 3, no.1, p. 101104 (2022). doi:10.1016/j.xpro.2021.101104.
2021
Kaljevic, Jovana ; Saaki, Terrens Norus Vargio ; Govers, Sander ; Remy, Oph茅lie ; van Raaphorst, Renske ; Lamot, Thomas ; Laloux, 骋茅谤补濒诲颈苍别. Chromosome choreography during the non-binary cell cycle of a predatory bacterium. In: Current biology, Vol. 31, no. 17, p. 3707-3720.e5 (2021). doi:10.1016/j.cub.2021.06.024.
2021
Kaljevic, Jovana ; Saaki, Terrens Norus Vargio ; Govers, Sander ; Remy, Oph茅lie ; van Raaphorst, Renske ; Lamot, Thomas ; Laloux, 骋茅谤补濒诲颈苍别. Uncovering the choreography of the chromosome during the non-binary cell cycle of the predatory bacterium Bdellovibrio bacteriovorus. In: bioRxiv, (2021). doi:10.1101/2020.12.21.419010.
2020
Laloux, 骋茅谤补濒诲颈苍别. Shedding Light on the Cell Biology of the Predatory Bacterium.. In: Frontiers in microbiology, Vol. 10, p. 3136 (2020). doi:10.3389/fmicb.2019.03136.
2019
Delhaye, Antoine ; Collet, Jean-Fran莽ois ; Laloux, 骋茅谤补濒诲颈苍别. A Fly on the Wall: How Stress Response Systems Can Sense and Respond to Damage to Peptidoglycan.. In: Frontiers in cellular and infection microbiology, Vol. 9, no.-, p. 380 (2019). doi:10.3389/fcimb.2019.00380.
2019
Delhaye, Antoine ; Laloux, 骋茅谤补濒诲颈苍别 ; Collet, Jean-Fran莽ois. The lipoprotein NlpE is a Cpx sensor that serves as a sentinel for protein sorting and folding defects in the envelope.. In: Journal of bacteriology, Vol. 201, no. 10, p. e00611-18 (2019). doi:10.1128/JB.00611-18.
2018
Hussein, Nahla A ; Cho, Seung-Hyun ; Laloux, 骋茅谤补濒诲颈苍别 ; Siam, Rania ; Collet, Jean-Fran莽ois. Distinct domains of Escherichia coli IgaA connect envelope stress sensing and down-regulation of the Rcs phosphorelay across subcellular compartments.. In: PLoS Genetics, Vol. 14, no.5, p. e1007398 (2018). doi:10.1371/journal.pgen.1007398.
2017
Laloux, 骋茅谤补濒诲颈苍别 ; Collet, Jean-Fran莽ois. Major Tom to ground control: how lipoproteins communicate extra-cytoplasmic stress to the decision center of the cell. In: Journal of Bacteriology, Vol. 199, no. 21, p. e00216-17 [1-13] (2017). doi:10.1128/JB.00216-17.
2016
Arts, Isabelle S. ; Vertommen, Didier ; Baldin, Francesca ; Laloux, 骋茅谤补濒诲颈苍别 ; Collet, Jean-Fran莽ois. Comprehensively Characterizing the Thioredoxin InteractomeIn VivoHighlights the Central Role Played by This Ubiquitous Oxidoreductase in Redox Control. In: Molecular and Cellular Proteomics, Vol. 15, no.6, p. 2125-2140 (2016). doi:10.1074/mcp.M115.056440.
2016
Delhaye, Antoine ; Collet, Jean-Fran莽ois ; Laloux, 骋茅谤补濒诲颈苍别. Fine-Tuning of the Cpx Envelope Stress Response Is Required for Cell Wall Homeostasis in Escherichia coli.. In: mBio, Vol. 7, no. 1, p. e00047-16 (2016). doi:10.1128/mBio.00047-16.
2015
Beaufay, Fran莽ois ; Coppine, J茅r么me ; Mayard, Aur茅lie ; Laloux, 骋茅谤补濒诲颈苍别 ; De Bolle, Xavier ; Hallez, R茅gis. A NAD-dependent glutamate dehydrogenase coordinates metabolism with cell division in Caulobacter crescentus. In: The EMBO journal, Vol. 34, no.13, p. 1786-1800 (2015). doi:10.15252/embj.201490730.
2014
Cho, Seung Hyun ; Szewczyk, Joanna ; Pesavento, Christina ; Zietek, Matylda ; Banzhaf, Manuel ; Roszczenko, Paula ; Asmar, Abir ; Laloux, 骋茅谤补濒诲颈苍别 ; Hov, Ann-Kristin ; Leverrier, Pauline ; Van DerHenst, Charles ; Vertommen, Didier ; Typas, Athanasios ; Collet, Jean-Fran莽ois. Detecting Envelope Stress by Monitoring 尾-Barrel Assembly. In: Cell, Vol. 159, no.7, p. 1652-1664 (28 dec 2014). doi:10.1016/j.cell.2014.11.045.
2014
Deghelt, Micha毛l ; Mullier, Caroline ; Sternon, Jean-Fran莽ois ; Francis, Nayla ; Laloux, 骋茅谤补濒诲颈苍别 ; Dotreppe, Delphine ; Van der Henst, Charles ; Jacobs-Wagner, Christine ; Letesson, Jean-Jacques ; De Bolle, Xavier. G1-arrested newborn cells are the predominant infectious form of the pathogen Brucella abortus. In: Nature Communications, Vol. 5, p. 4366 (2014). doi:10.1038/ncomms5366.
2014
Laloux, 骋茅谤补濒诲颈苍别 ; Jacobs-Wagner, Christine. How do bacteria localize proteins to the cell pole?. In: Journal of Cell Science, Vol. 127, no.1, p. 11-19 (1/1/2014). doi:10.1242/jcs.138628.
2013
Laloux, 骋茅谤补濒诲颈苍别 ; Jacobs-Wagner, Christine. Spatiotemporal control of PopZ localization through cell cycle-coupled multimerization. In: The Journal of Cell Biology, Vol. 201, no.6, p. 827-841 (10/06/2013). doi:10.1083/jcb.201303036.
2011
de Barsy, Marie ; Jamet, Alexandre ; Filopon, Didier ; Nicolas, C茅cile ; Laloux, 骋茅谤补濒诲颈苍别 ; Rual, Jean-Rual ; Muller, Alexandre ; Twizere, Jean-Claude ; Nkengfac, Bernard ; Vandenhaute, Jean ; Hill, David E. ; Salcedo, Suzana P. ; Gorvel, Jean-Pierre ; Letesson, Jean-Jacques ; De Bolle, Xavier. Identification of a Brucella spp. secreted effector specifically interacting with human small GTPase Rab2. In: Cellular Microbiology, Vol. 13, no.7, p. 1044-1058 (2011). doi:10.1111/j.1462-5822.2011.01601.x.
2010
Laloux, 骋茅谤补濒诲颈苍别 ; Deghelt, Micha毛l ; de Barsy, Marie ; Letesson, Jean-Jacques ; De Bolle, Xavier. Identification of the essential Brucella melitensis porin Omp2b as a suppressor of Bax-induced cell death in yeast in a genome-wide screening.. In: PLoS One, Vol. 5, no.10, p. e13274 (2010). doi:10.1371/journal.pone.0013274.
2009
Dreze, Matjia ; Charloteaux, Benoit ; Milstein, Stuart ; Vidalain, Pierre-Olivier ; Yildirim, Muhammed A ; Zhong, Quan ; Svrzikapa, Nenad ; Romero, Viviana ; Laloux, 骋茅谤补濒诲颈苍别 ; Brasseur, Robert ; Vandenhaute, Jean ; Boxem, Mike ; Cusick, Michael E. ; Hill, David E. ; Vidal, Marc. 'Edgetic' perturbation of a C. elegans BCL2 ortholog. In: Nature Methods, Vol. 6, no. 11, p. 843-849 (2009).